Episode "Demon with a Glass Hand" (1964) from the TV Show "The Outer Limits", Season 2 Episode 5.
In the future the Earth has been invaded by an extraterrestrial race called Kyben. Unable to cope with its technological and weapons superiority, the human race leaves the planet unleashing an epidemic that leaves the world uninhabitable. The last human being on Earth, an individual named Trent, is an amnesic man, without a past, who has an artificial crystal hand connected to his brain.
